Novel research helping us understand the mechanism of miscarriage

An important new paper has been published in the open access journal PLOS ONE in relation to recurrent miscarriage (RM). Weimer et al have shown that there are differences in the migration patterns of endometrial stromal cells in women with and without a history of RM. In controls, the presence of a poor quality embryo […]

Fertility and recurrence after treatment for ectopic pregnancy

The two questions asked first by most women who have had an ectopic pregnancy are “how will this impact on my future fertility” and “what are the chances of me having an ectopic pregnancy in a future pregnancy”. A new study published in the journal Fertility and Sterility from the research group in Clermont Ferrand […]

Serum Biomarkers for Detecting Ectopic Pregnancy

Abstract Unless an ectopic pregnancy is visible by ultrasound, diagnosis can be a challenge. Differentiating ectopic pregnancies from intrauterine pregnancies can be impossible without intervention or follow-up. This poses a clinical dilemma to the practitioner given the inherent danger to the mother of tubal rupture of an ectopic pregnancy versus the fear of intervening in […]

Reproductive Outcomes After Medical and Surgical Management of Ectopic Pregnancy

Abstract Ectopic pregnancies have a negative impact on future fertility. Prompt diagnosis is paramount to preserve tubal function and reproductive potential. Expectant, medical, and surgical management of ectopic pregnancies have similar efficacy in properly selected patients. Medical management has emerged as a safe alternative to surgery and holds promise for preservation of future fertility. Laparoscopic […]

A Review of the Literature Regarding Expectant Management of Ectopic Pregnancy.

Abstract This article will provide a review of the literature regarding expectant management of ectopic pregnancy. Detailed definitions and methods of evaluation are discussed, as well as pooled existing data on success rates of expectant management. A comparison of expectant management versus other treatment options is provided as well as a review of fertility outcomes […]

The METEX Study: Methotrexate vs Expectant management

The METEX study: Methotrexate versus expectant management in women with ectopic pregnancy: A randomised controlled trial To study whether expectant management is an alternative to treatment with systemic MTX in a single dose im regimen in women with an EP and low but plateauing serum hCG concentrations in terms of tubal rupture, future pregnancy, health […]